Expanded Range of Laminin isoforms
Aug 16 2022
Efficient cell culture and differentiation of ES/iPS cells
Designed to efficiently induce differentiation in ES and iPS cells,AMSBIOhas expanded itsiMatrix series of recombinant laminin E8 fragmentsto now include isoforms LN-111 and LN-332.
This expanded range of laminin isoforms (LN-111, 332, 511, 411 and 221) now provides even greater flexibility and control when tailoring your substrate to the requirements of specific cultured cells.
Dual advantage of recombinant protein expression
Proven in many leading life science research labs - iMatrix is used as a substrate for culturing and maintaining cells, including Pluripotent Stem Cells and Mesenchymal Stem Cells, as well as for differentiation into ectoderm, endoderm, and mesoderm. All iMatrix products offer the dual advantage of recombinant protein expression and as E8 fragments they contain all of the integrin-binding sites of full-length laminin in a much shorter protein.
Differentiation of iPSCs into hepatocyte-like cells
New to the product range, iMatrix-111 is the E8 fragment of the LN-111 isoform, which plays significant roles in vivo and is important in cell culture. As well as being the major substrate for nerve axon growth, both in vivo and in vitro, LN-111 is also the main component of the industry standard substrates used in cell culture: Matrigel® and Cultrex® BME. iMatrix-111 has been validated for to promote differentiation of iPSCs into hepatocyte-like cells.
The Laminin-332 isoform is essential for epithelial cell adhesion to the basement membrane and iMatrix Laminin-322 has been used to induce differentiation of iPS cells into corneal epithelial cells in vitro.
Stem Cell Synergy Solution
AMSBIO also offers a comprehensive range ofsynergistic high performance stem cell productsfor streamlined and efficient ES/iPS cell culture for basic to clinical research.
Digital Edition
Lab Asia 29.4 - August 2022
August 2022
In This Edition Chromatography - Automated Sample Preparation:The Missing Hyphen to Hypernation - New Low Volume Air Sampler for PFAS Analysis - Analytical Intelligence Starts with the Samp...
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Events
ACS National Meeting & Expo, Fall 2022
Aug 21 2022Chicago, IL, USA & Online
Aug 22 2022Frankfurt, Germany
Aug 27 2022Maastricht, Netherlands
Aug 28 2022Lisbon, Portugal
Aug 31 2022Singapore